The Buff Alligator is a rare spawn in the Sewers area, and an Elite version of the Alligator enemy. In addition to increased stats compared to the normal Alligator, the Buff Alligator wields a Flak Cannon, which fires a single small red orb that after traveling a short distance or hitting a wall, splits into 10 red pellets. Upon impact with the orb the player takes damage from all 10 pellets and the orb itself which results in an instant 14 damage.

Buff Alligator is much more aggressive than the regular Alligator. It won't hide behind cover and instead it will actively pursue after the player while shooting.

Although mostly encountered in the Sewers, Buff Alligators can sometimes be found in the Crystal Caves by destroying the Cocoon prop.